Spoiler Alert: These essays are ideally to be read after viewing the respective films.
Showing posts with label medicine. Show all posts
Showing posts with label medicine. Show all posts

Friday, November 24, 2023

The Exorcist

One of the most iconic films of the horror-film genre, The Exorcist (1973) focuses on the duality of good and evil that the film’s director, William Friedkin, maintained is in a constant struggle in all of us. The dialogue between the two priests performing the exorcism on the one side and the Devil possessing Regan on the other not only reveal the duality, but also the essence of evil itself. Once this essence is grasped, interesting questions can be asked that are distinctly theological, as distinct from modernity’s trope of evil portrayed in terms of, and even reduced to, supernatural movements of physical objects. The decadent materialist version of the theological domain stems from modernity’s bias in favor of materialism and empiricism. In other words, highlighting supernatural physics as being foremost in representing the religious realm is how secularity sidelines religion, rather than how religion itself is. The bias of modern society is very clear in the film as the “professionals” go through alternative explanations first from the field of medicine, privileging the somatic (physical) and then the psychological domains of medicine. In other words, the narrative establishes (or reflects) a hierarchy of three qualitatively different levels of descending validity: the somatic is primary, and only then the psychological, and, if the first two do not furnish an explanation, then, and only then, are we to turn to the theological as metaphysically (i.e., supernaturally) real primarily shown by physical objects defying the laws of physics. Science, rather than religion, is thus still in the driver’s seat. The bias in favor of materialism is in the assumption that only after feasible hypotheses from modern medicine are nullified can theological explanations be considered (as credible). In this way, the film reflects the hegemony of materialism that has taken hold since the Enlightenment, and the relegation of the theological as “magical” supernaturalism, as in a bed levitating of objects flying around Regan’s bedroom. The essence of evil is instead interior. If religion is a matter of the heart, then how could evil be otherwise?

In the film, the physicians searching for the cause of Regan’s bizarre behavior initially believe that a lesion in the girl’s frontal lobe is the cause. The two physicians are so preoccupied with a somatic (i.e., physical) cause that they ignore the mother’s account of the supernatural shaking of Regan’s bed. One of the physicians insists, “I don’t care about the bed!” The monopolization of the physical medically is here being ridiculed by the filmmaker, for it is ridiculous to ignore a bed whose jumping around so obviously surpasses the physical strength of a child. Secular modernity is being portrayed as defiant, even ideological in the very least in being narrow-minded and petulant and obstinate like a spoiled child.

When no lesion is found, the physicians recommend that a psychiatrist be consulted. Even then, the obvious indications of the involvement of a supernatural entity or force are dismissed. Implicitly, religion is reduced to psychology. It is as if Rudolf Otto’s text, The Idea of the Holy, could be reduced to Sigmund Freud’s Totem and Taboo. In the film, the priest Karras is a pastoral counselor, and he is brought in precisely for his knowledge of psychology. So when the possibility of psychosis can be excluded and the psychiatrists recommend that a priest be consulted to perform an exorcism, Regan’s mother Chris brings in Karras. Bridging both worlds, he confronts his own lack of faith by admitting to himself that Regen really is possessed by a demon. The elder priest, Merrin, is firmly in the theological domain, and so he has no doubt that he is battling a supernatural being of pure evil.

We have finally reached the theological level, having dispelled medicine in its two major categories. Karras’ loss of faith is no more. Significantly, what ultimately convinces the guilt-ridden priest of the distinctly religious basis of Regan’s problem are not the shaking or levitating bed. Rather, Regan’s impossible interior knowledge is what convinces Karras that a being other than Regan exists in the possession. Only an entity other than Regan could know of Karras’ guilt regarding his recently deceased mother and be able to speak English in reverse as well as in Latin. These interior signs are more important to the theological domain than are the physical (i.e., materialism) manifestations of the bed levitating and objects flying around Regan’s bedroom. The latter titillating optical displays make good movie-viewing but are hardly in themselves evil, whereas tormenting a priest about his guilt is because evil is the opposite of love.

Nonetheless, Hollywood has focused on how and whether to depict the Devil empirically—as yet another object that can be seen. In the film, The Ninth Gate (1999), the presence of the Devil is shrouded in bright light, contradicting the commonly held notion that evil lies in darkness because it is absent from the light of God’s truth. The viewers never get to see the Devil. In Rosemary’s Baby (1968), the Devil is only visible in one scene, when the beast rapes Rosemary. As in The Ninth Gate, the essence of evil is not depicted; the interior life of the supernatural being is not revealed even though it is much closer to the essence of evil. Likewise, in Poltergeist (1982), the characters’ astonishment is at how the souls and the supernatural entity appear visually.

The Exorcist is an improvement on those films in that even though the Devil itself is not shown (except in an archeological sculpture), its mentality is clear from how it relates to the priests through the dialogue. The blinding white light depicted in The Ninth Gate, the animalistic look of the Devil in the rape scene in Rosemary’s Baby, and the levitating bed and flying objects in The Exorcist do not do justice to the theological realm; in fact, they are distractions. They reveal modernity’s warped caricature of religion in reducing it to carnival tricks. The science of medicine can easily be viewed as superior. The emphasis on the empirical is itself in line with the materialist orientation of modernity. In simpler terms, depicting the theological in terms of physical objects is in service to the preference for modern (empirical) science. I submit that the nature or essence of religion is not material or physical; rather, the essence can be found in sentiments like love and hate.

It is in the dialogue between the Devil and the priests that The Exorcist goes beyond the other films in depicting the nature of evil, and thus of the Devil. That the entity possessing Regan enjoys tormenting the two priests is much more important than what the Devil looks like, or that it makes Regan’s bed levitate.

Once presented with the Devil’s nature, movie-goers can come away from the movie thinking theologically on theology’s own terms rather than on those belonging and pertaining to a qualitatively different domain (e.g., the natural sciences). For example, viewers might consider whether the Devil’s mentality, as depicted in the film, could be loved. Here, a crucial distinction must be made to avoid a Satanist (i.e., pro-evil) misinterpretation.  For the two exorcist priests to love the entity possessing Regan, they would be ministering to the entity with the intention of saving the mentality from itself or else riding the entity of the sordid mentality. Support for the claim that evil can be ministered to exists in  the Christian Bible.

In the Gospels, Jesus says of the evil men responsible for having him crucified, Forgive them, for they know not what they do. Rather than approving or loving their evil mentality, he is forgiving them for having it. In publicly pronouncing his forgiveness, he is ministering even to them, and as a result it is possible, given free will, that even they could be saved from themselves (i.e., the evil mentality). What if Jesus were to minister to the Devil tempting him in the desert? Can an entity whose very essence is the mentality be the recipient of a loving, unconditional heart?

On the ministering side, agape, or selfless love, is unconditional, and for this to hold, an entity that is evil cannot be excluded even if it excludes itself. Even caritas, Augustine’s interpretation of Christian love (derived from Plato’s love of the eternal moral verities) that includes self-love albeit sublimated to having God as its object, is universal benevolence. Caritas seu benevolentia universalis, according to Augustine. A good will (benevolentia) is not universal (universalis) if even the most squalid entity is excluded as an object of the love qua benevolence.

On the Devil’s side, can such an entity be rid of its mentality? I submit that it can, and thus the evil mentality is not the essence of the entity. Because Lucifer falls from grace, the fallen angel (i.e. the Devil) was once without the cold mentality. Therefore, that mentality cannot be the Devil’s essence. The entity can be distinguished from, and thus rid of, its current mentality.  

In The Exorcist, imagine if the two priests were to pray for the Devil’s soul even as the entity enjoys tormenting the two men. Forgive it, for it knows not the love of God. This is the perspective that enables a ministering to rather than an acceptance or approval of the mentality. What if the priests were willing to sacrifice their lives to save the Devil and not just Regan? It seems that the battle against evil would be won by unconditional love, but would the battle metaphor even fit were the priests ministering to the Devil rather than merely getting it to leave by shouting at it?  This would not be to love the mentality as if it were something to be praised; rather, it would be to state that love can not only survive death for the faithful, but also reach into the cold darkness of deep space devoid of God’s presence.

A young Satanist once told me that he loves Satan. “Then God is present in you after all,” I replied, “because God is love.” Love can reach into places that are presumably beyond God, where hatred reigns. Of course, it is one thing for a Satanist to feel love, even though misdirected to an entity with an evil mentality, and quite another for that entity to let go of its all-consuming hatred, ultimately, of God. In the Gospels, not even the Crucifixion dislodges the entity’s mentality from Jesus’ antagonists.

In the television mini-series, Jesus of Nazareth (1977), several members of the Jewish hierarchy in Jerusalem, the Sanhedrin, show no remorse even while hearing Jesus quoting from the Hebrew scripture while suffocating on a cross. One of the members says, “Even now, while nailed to a cross, he quotes from scriptures. Even now.” What would it take for the official’s astonishment at the sincerity of Jesus’ selfless piety to trigger a recognition of the wrong that he had just committed against an innocent person whose piety is evinced even under such extreme duress? After the Crucifixion, a Roman centurion who tortured Jesus rebukes Zerah, a scribe of the Sanhedrin who had instigated Jesus’ arrest, for continuing his obsession against Jesus. Not even having Hebrew guards stationed at the tomb are enough, Zerah insists, because Jesus’ disciples could lie that Jesus has risen, so Roman guards are necessary. After listening to Zerah’s relentless conspiracy theory, the centurion remarks, “What sort of person are you, if I may ask? His death is not enough for you.” Theologically, the message is that intractable stubbornness can continue to hold up complicity in the suffering and death of Jesus. By implication, the Devil surely is not touched by Jesus’ vicarious sacrifice on behalf of others. However, if enough people use the Crucifixion in the narrative as a model and instantiate it in their own confrontations with evil in other people, perhaps it will lose its force even where it is strongest. In other words, perhaps if instead of fighting against evil, we minister to those whose mentality is evil, the very notion of battle will dissolve, and with it, evil too.

In the film Mary Magdalene (2018), Mary Magdalene refutes Peter’s conception of the Kingdom of God as awaiting the Second Coming for the people to rise and Jesus be crowned king so Roman rule would finally be vanquished. “Jesus never said he would be crowned king,” she tells the disciples. “The kingdom is here, now,” she explains in dispelling the disciples’ misinterpretation of Jesus’ preaching on the Kingdom. The disciples see no kingdom because the Roman occupation has not ended, but she insists that “it’s not something we can see with our eyes; it’s here, within us. All we need to do is let go of our anguish and resentment and we become like children, just as he said. The Kingdom cannot be built by conflict, not by opposition, not by destruction; [rather] it grows with us, with very act of love and care, with our forgiveness.” Apply this rendering of the Kingdom of God to Jesus’ commandment to love one’s enemies and we have a kingdom ultimately built by ministering to one’s enemies, including coming to their aid, and, in so doing, vanquish our own hatred. Our foremost enemy is the mentality of evil. A person letting go of one’s own anguish and resentment first means letting go of that interior mentality, which is a prerequisite to changing the world by loving one’s enemies. In actuality, coming to the aid of one’s enemies can dissipate one’s own interior mentality of evil and thus bring inner peace, so the causal relationship goes in both directions. A person does not have to be at peace in order to extend love to one’s external enemies by ministering to them and thus dissipating external conflict, but having let go of one’s own hatred certainly helps.

In the Exorcist, the Devil tortures the priest Karras by reminding him of his guilt about having consigned his mother to a nursing home. Karras resists the Devil’s manipulation rather than views it as an opportunity to let go of the anguish. He could say, You know, you’re right. I screwed up, but I’m only human and I’m sorry. I do love my mother. He could then let the anguish go. Furthermore, he could pivot to ministering to his enemy’s anguish in feeling rejected by God. That would surely unleash fury. How dare you minister to me! It is pertinent to ask, what if one (or both) of the priests were to sacrifice his life while ministering as loving the enemy? That would be to instantiate the model of the Crucifixion. “Forgive them, for they know not what they do” extends that model even to the benefit of enemies. Could even the Devil’s cold heart ignore that model being applied for the Devil itself? The answer, it seems to me, hinges on whether the Devil’s evil mentality is the Devil’s essence or merely an attribute; of the two, only the latter can be changed. I have in mind here Aristotle’s distinction between substance and accident. I submit that an entity of the sort that can have a mentality can be distinguished from a mentality because of free-will, which pertains to such an entity rather than to a mentality. If this is so pertaining to the Devil, then surely people who have an evil mentality can be ministered to from the standpoint of unconditional love as benevolentia universalis applies to one’s enemies.

The preceding thought experiment on whether the Devil can be saved from itself is distinctly theological. We aren’t thinking about Regan’s possession in terms of her bed violently jumping and levitating. In being valid in its own right and on its own terms, thinking distinctively theologically relegates and perhaps even defeats the secular primacy of the world of physical objects, and thus materialism. The audacious and derisive encroachment on religion even to the point of rendering it as something primarily physical, empirical, and material, rather than as interior to the human condition, is accordingly pushed back. The essence of religion can be investigated and discovered on its own terms and thus rendered more accurate and complete.

Wednesday, May 17, 2017

Realive

In 2016, Robert McIntyre, a graduate of MIT, became the first person to freeze and then revive a mammalian brain—that of a white rabbit. “When thawed, the rabbit’s brain was found to have all of its synapse, cell membranes, and intracellular structures intact.”[1] The film, Realive, made that same year, is a fictional story about a man with terminal cancer who commits suicide to be frozen and revived when his illness could be cured. In the context of McIntyre’s scientific work, the film’s sci-fi demeanor belies the very real possibility that cryogenics could realistically alter fundamental assumptions about life and death even just later in the same century. What the film says about the life and death is timeless, however, in terms of philosophical value.




Diagnosed with inoperable brain cancer, Marc Jarvis opts for cryogenics. His body is to be frozen and revived when technology has advanced to the point of being able to reanimate him and cure the cancer. “I’d be able to live longer,” he blandly tells his friends, who are skeptical. For this to happen, he responds, “I guess I’d have to trust humanity.” He is referring to the advent of the necessary medical technology, rather than to the question of whether global climate change might extinguish the species in the meantime. This “sin of omission” by the screenwriter is particularly strange, given physicist Steven Hawkins’ prediction at the time that the species would have at most a century left on a habitable Earth.

In the story, living longer isn’t Marc’s actual goal, so he may well be indifferent to the plight of the species as he informs his friends of his decision to go with cryogenics. He does not commit suicide with the hope of being revived when he could be cured so he could live out the rest of his life.  As he tells Elizabeth, his nurse after he is revived 60 years later, in 2084, “Suicide was my way of fighting the arbitrariness of cancer.” Suicide, he tells her, was “the only way of avoiding the agony and the uncertainty of when death would finally arrive.” In retrospect, he says that being able to end his life at his choosing gave him the power to die peacefully. He had not really thought he could be reanimated; suicide, he tells Elizabeth, “gave me back control over my life.” He had accepted death; things were fine as they were. He accepted his experience of life as that which it had been, even though he was still young (roughly 30). The fear was gone, he tells Elizabeth more than 100 arduous days after having being revived. His fear of death is still gone, he informs her as he then asks her to help him commit suicide again. He has already died once. He is once again prepared to end his life. His final wish: “To be nothing again, to disappear, to finally rest in peace.” Why? To return to an after-life existence in heaven? Or out of a preference for not existing over the pain of living?

Just after being revived, he is enthusiastic. “I was going to die,” he tells the medical team in front of his bed. “I was going to disappear, forever, and I’m alive again. I’m alive!” But he quickly realizes that his “new life” comes with some rather serious drawbacks, medically speaking. At least for some weeks, his body seems permanently “on the verge of collapse.” He records the following for future posterity: “Life, what do we expect from it? Certainly not this fragility, this half-speed existence. We definitely don’t expect a medical history full of afflictions and minor defects, a propensity for phlegmbosis, numbness in the extremities, involuntary movements, loss of equilibrium, scaling of the skin, irritation of connective tissue, respiratory insufficiency, cardiac insufficiency, incontinence, impotence. You don’t expect so many limitations so soon.” His physician tells him that he could expect a life like people with chronic diseases or the elderly, and he would have to maintain at least periodic connection to a machine that keeps him alive. In erroneously assuming that these conditions would be permanent, both Marc and his physician dismiss the likelihood that medical science would continue to advance. 

To be sure, Marc’s medical team knew Marc would lose all of his memories, after which no medical science could bring them back. You expect at least to keep your memories, Marc narrates for posterity. “What if your memories were erased as well? What will become of me once my memories have faded?” Fortunately, a device exists in 2084 that can allow people to recover memories without actually remembering anything, but he dismisses it outright too. He could still draw on those stored memories mentally—hence indistinguishable from him really having the memories—and perhaps advancements in medical science could literally grow more “gray matter” such that Marc would someday begin to accumulate new memories. In short, the static nature in the assumptions made not only by Marc, but, more astonishingly, by his medical term in 2084 is astonishing, given their experiences with medical advancements.

At any rate, Naomi, Marc’s girlfriend before he died, had herself frozen in hopes of being together with her true love again someday. Elizabeth wants to assure Marc, “Someday you two will be able to be together again like you were before; it’s only a matter of time.” Here in Elizabeth we find the openness of a dynamic assumption; medical science should be regarded as a moving target!  Yet he isn’t buying it. He knows Naomi’s bodily condition is not good; the process of freezing had not gone well. “I don’t even want to imagine Naomi if she’s trapped in someone else’s body, someone else’s life,” he tells Elizabeth. “That’s your fear talking,” Elizabeth correctly tells him. In short, Marc has lost hope—faith in medical science and even in life itself. Accordingly, he wants to commit suicide again, and he wants Elizabeth to bracket her own hope and assist him.

The nineteenth-century European philosopher, Ludwig Feuerbach, aptly describes Marc’s rationale for killing himself “for good” (i.e., without any hope of being reanimated again). “A man who kills himself does not take his life, it has already been taken from him. That is why he kills himself; he destroys only a semblance of himself; what he casts away is a mere shell whose kernel, whether by his fault or not, has long since been eaten away. But a healthy, normal life . . . is and should be man’s highest good, his supreme being.”[2] Marc expects a healthy, normal life; it is his god. Yet paradoxically death is not his enemy, for suicide is to him simply a preference for not existing over life without his god.

Life and death are of course the true characters in the fictional drama. Expectedly, religion is in the mix, though surprisingly only explicitly in a few instances in the film. The position taken in the film, through Marc as a witness—albeit fictional—is that life “is nothing more than a state of matter . . . there’s nothing transcendent or divine about it.” As such, life is merely biological. In fact, Marc opines that it is life that’s “scary, not death.” Life is “always on the verge of extinction.” A human life can quickly, and unexpectedly end without the person having any control over it. As for the soul, Marc figures it is maybe “the part that is lost when you freeze the meat and thaw it out again.” In short, the film adopts a materialist perspective. There is no after-life, other than revitalized, or unfrozen, life itself. In other words, being reanimated—not resurrected!—is the only after-life, or, more accurately, life after life. In between them: nothing. Not existing. How hard this is to apply to ourselves!

“Welcome back to life, Marc,” the physician says as Marc regains consciousness upon being revived. “Do you remember anything about the other side?” Is there an afterlife?, the physician wants to know. The first report of a possible “eye-witness” of heaven in human history is underwhelming: “Fear, dying, waking up,” Marc answers without a hint of excitement. Later, he makes it explicit: “Before I died, I thought there was nothing after death. Now I’m sure.” He is the only person alive immune from what Feuerbach describes as the fantasies of profligate human imagination. Marc records his (or the screenwriter’s) own thoughts as follows: “Why do we yearn so desperately for life after death? What is it that we want? Perhaps reward for our grief, or punishment for our sins. No, what we really expect to find is what we already know; what we once had and lost. If there was something, we would turn it into more of the same—the same chaos and the same beauty, the same reward for the same effort, the same tale by the same idiot. If there was something, it would probably be purgatory.” In other words, we construct, or hope for, an after-life looking all too familiar—human, all too human. The “most sensitive, most painful of man’s feelings of finiteness is the feeling or awareness that he will one day end, that he will die,” Feuerbach suggests.[3] All a person knows and experiences is premised on the ongoing—perceptually-seeming “ever” present—basis of existing, the end of which must surely be felt to be torrentially horrendous. A human’s “defense against death is the belief in immortality.”[4] People who think they know for a fact there is an afterlife might want to pause at word in italics. None of us know, which is why the screenwriter of the film has Marc’s physician ask.

The physician—a man of science!—is disappointed in Marc’s answer as it is well within the realm of biology. He wants for there to be a religious dimension so much that he over-reaches cognitively. In presenting Marc to the public (i.e., investors), for example, he refers to Marc as “the first person resurrected.” However, resurrection is a distinctively religious term that refers to a spiritual-physical body; Jesus’ resurrected body, for instance, goes through the door of the Upper Room and yet he is hungry so he asks for a fish! Clearly, more is going on here than reanimation or revitalization. Cryogenics does not even constitute the sort of miracle as Jesus performed in bringing Lazarus back to life, and yet Marc's physician refers to his successive cryogenic attempts, including Marc, as Lazarus!

In short, Marc’s (albeit fictional) body is not supernatural, and yet the physician uses terms suggestive of a religious miracle. In fact, he refers to Marc as the first resurrected man more than once in the film. It is as if man of science were driven instinctually to make what is human, divine. According to Feuerbach, “Man makes a god or divine being of what his life depends on only because to him his life is a divine being, a divine possession or thing.”[5] God is beneficent (because good), and thus of use to humans—hence petitions are made as a matter of course in many liturgies, but the underlying presupposition or basis of this belief in the divine attribute is that human life is itself of great worth (i.e., divine).

Therefore, Marc while still young and yet seemingly deprived of God’s beneficence has a knee-jerk reaction for his life to go on, albeit after some time of not existing. Alternatively, he could pin his hopes on heaven, yet he dismisses it even before he knows it to be a fantasy of the human imagination tinged with fear. Yet even in ostensibly wanting to live more, or again, it is to be on his terms.

According to Feuerbach, we are the gods—or, more accurately—our human ideals are our true gods—the potential of the species, which Feuerbach erroneously claimed is infinite. The danger in idolizing our ideals lies in settling for nothing less. Hence Marc acts rashly, I submit, in committing suicide again. His god is human, all too human. If Feuerbach was right, even the ostensibly religious deity is really just human life in its infinite potential. Yet the terrain of our experience is finite—our perception, feeling, and cognition only go so far. Even cryogenics in itself could merely extend a human life, rather than making human beings immortal.

 




[2] Ludwig Feuerbach, Lectures on the Essence of Religion (New York: Harper & Row, 1967), 52.


[3] Ludwig Feuerbach, Lectures on the Essence of Religion (New York: Harper & Row, 1967), 33.


[4] Ibid., 34, italics added.


[5] Ibid., 52.

Friday, June 5, 2015

The Age of Adaline: Death as No Longer Inevitable

In The Age of Adaline (2015), the age-old “fountain of youth” leitmotif springs forth yet again. In this incarnation, Adaline is forced to come to grips with the fact that everyone around her, including her daughter, is aging even as Adaline herself does not. A strong electromagnetic has altered her genes such that her cells do not divide at slower rates as they age. As she becomes aware of the repercussions, we in turn can marvel at what may be just decades away scientifically concerning the expected human life-span. In short, when the film came out, scientists were already openly discussing whether death itself may no longer be inevitable for human beings.


In an article in Biomaterials published in August 2015, scientists from the Ott lab at Harvard University provide the world with the science behind their successful effort to grow a rat’s limb from cells and attach it to a living rat.[1] Harald Ott describes the significance of the scientific feat for human beings. “Limbs contain muscles, bone, cartilage, blood vessels, tendons, ligaments and nerves – each of which has to be rebuilt and requires a specific supporting structure called the matrix. We have shown that we can maintain the matrix of all of these tissues in their natural relationships to each other, that we can culture the entire construct over prolonged periods of time, and that we can repopulate the vascular system and musculature. . . . Additional next steps will be replicating our success in muscle regeneration with human cells and expanding that to other tissue types, such as bone, cartilage and connective tissue.”[2] In other words, a person’s diseased or simply aged organs may one day be replaceable with organs grown with the individual’s own cells.

The Ott lab’s mission statement lays out the rationale. “End organ failure is the leading health care challenge in the Western World. Nearly 6 million Americans suffer from heart failure with about 550,000 new cases diagnosed annually; 25 million Americans suffer from chronic obstructive pulmonary disease (COPD) with an estimated 12 million new yearly diagnoses; 530,000 Americans suffer from end stage renal disease. Organ transplantation is the only potentially curative therapy available. However, its outcomes are limited by donor organ shortage and the side effects of harsh immunosuppressive treatments. Organ engineering is a theoretical alternative to transplantation. Whole organs could be derived from patient’s cells and transplanted similar to donor organs.”[3] If the brain is such an organ and could be grown from a person’s cells, then would such a transplant essentially end one person, or at least consciousness, and begin another? Ethically speaking, who would have access to his or her own personal “replacement organs”? Only the rich, while death is still inevitable for the poor and middle class?

To be sure, a bunch of organs does not a body make; considerably more is involved. So we must look to the research on cellular aging itself before we can anticipate death as not necessarily inevitable. Just to clarify, this is not the same as immortality. In the film, for example, were Adaline to get hit by a truck, she would not continue at the same age; she would be dead.

In 1913, researchers discovered a cause of aging in mammals that may be reversible.[4] “The aging process we discovered is like a married couple—when they are young, they communicate well, but over time, living in close quarters for many years, communication breaks down,” said Harvard Medical School Professor of Genetics David Sinclair, senior author on the study. “And just like with a couple, restoring communication solved the problem.”[5] In scientific terms—now that I’ve warmed you up—“The essence of this finding is a series of molecular events that enable communication inside cells between the nucleus and mitochondria. As communication breaks down, aging accelerates. By administering a molecule naturally produced by the human body, scientists restored the communication network in older mice. Subsequent tissue samples showed key biological hallmarks that were comparable to those of much younger animals.”[6] That is, not only can the aging process be slowed down; it can actually be reversed!

The implications of the research both in growing organs and reversing the aging process at a cellular level are nothing short of breathtaking, not to mention paradigm-altering. At the time of the film’s release, some scientists were openly suggesting that death might no longer be inevitable as early as 2050. That is to say, children, young adults, and even people having reached middle-age watching The Age of Adaline in early 2015 might not experience aging themselves, even as they would naturally have memories of grandparents or parents having aged and died.[7] In the film, Adaline must come to grips with her daughter being an old woman; the implication is that Adaline would eventually have to confront the loss of her daughter, and, indeed, anyone else held dear. I believe this is why Adaline keeps herself from getting into a romantic relationship; even more than wanting to avoid the fear of trusting another person with her secret (for fear of being picked apart by government scientists) and being in the awkward situation of being young while one husband after another reaches retirement age, the deaths of one dog after another—a photo of each one being solemnly kept in an album—have taught her that death as not inevitable has a very sad downside.

Even if death is rendered not inevitable (even as taxes remain so) for every person alive, say in 2100, people would experience other living beings aging and dying. Moreover, longevity itself would doubtless have its own downsides. For those to whom life is a terrible struggle, a lifespan of even just two hundred years—the time between 1776 and Jimmy Carter as the U.S. President in the late 1970s—could be felt to be a curse. The whole notion of a life sentence would have to be re-thought, otherwise it would be intolerably cruel. So too would age discrimination need to be reconsidered. Would it even make sense?

Furthermore, would everyone in the world be at the same age? If so, would humanity consist of children and adult-children—Munchkins, as it were, only with a youthful look? Such a sight would doubtless be extremely distressing to any aliens visiting from elsewhere in the galaxy. Perhaps people could decide to stay at any given age—presumably after having reached adulthood.

Moreover, the right to reproduce in an already overpopulated world might become contentious at least as pertaining to those persons who have “opted into” death as not inevitable, though even they could of course die from an accident or natural disaster. Ethicists would likely find work. The Age of Adaline only skims the surface of the implications from what may lie in store for humanity—that is, if our species can survive the climate-change that was already underway at the time of the film’s release. My point here is that we really have no idea what some of the implications would be; the medical advances touched on above, as well as the work on diseases such cancer, may outstrip the capacity, or at least the usual habits, of the human mind to adapt. At the very least, some paradigms with deep ruts may need to be buried and new seeds sowed.




[1] Bernhard Jank et al, “Engineered Composite Tissue as a Bioartificial Limb Graft, Biomaterials (August 2015), 61:246-56. The abstract reads as follows: “The loss of an extremity is a disastrous injury with tremendous impact on a patient's life. Current mechanical prostheses are technically highly sophisticated, but only partially replace physiologic function and aesthetic appearance. As a biologic alternative, approximately 70 patients have undergone allogeneic hand transplantation to date worldwide. While outcomes are favorable, risks and side effects of transplantation and long-term immunosuppression pose a significant ethical dilemma. An autologous, bio-artificial graft based on native extracellular matrix and patient derived cells could be produced on demand and would not require immunosuppression after transplantation. To create such a graft, we decellularized rat and primate forearms by detergent perfusion and yielded acellular scaffolds with preserved composite architecture. We then repopulated muscle and vasculature with cells of appropriate phenotypes, and matured the composite tissue in a perfusion bioreactor under electrical stimulation in vitro. After confirmation of composite tissue formation, we transplanted the resulting bio-composite grafts to confirm perfusion in vivo.”
[2] Nitya Rajan, “Scientists Grow an Entire Limb in the Lab Using a Dead Rat,” The Huffington Post, June 4, 2015.
[3]Our Mission,” The Ott Lab for Organ Engineering and Regeneration, Harvard University (accessed June 5, 2015).
[4] Ana Gomes et al, “Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging,” Cell (19 December 2013) Vol. 155, No. 7, pp. 1624-638. The abstract reads as follows: “Ever since eukaryotes subsumed the bacterial ancestor of mitochondria, the nuclear and mitochondrial genomes have had to closely coordinate their activities, as each encode different subunits of the oxidative phosphorylation (OXPHOS) system. Mitochondrial dysfunction is a hallmark of aging, but its causes are debated. We show that, during aging, there is a specific loss of mitochondrial, but not nuclear, encoded OXPHOS subunits. We trace the cause to an alternate PGC-1α/β-independent pathway of nuclear-mitochondrial communication that is induced by a decline in nuclear NAD+ and the accumulation of HIF-1α under normoxic conditions, with parallels to Warburg reprogramming. Deleting SIRT1 accelerates this process, whereas raising NAD+ levels in old mice restores mitochondrial function to that of a young mouse in a SIRT1-dependent manner. Thus, a pseudohypoxic state that disrupts PGC-1α/β-independent nuclear-mitochondrial communication contributes to the decline in mitochondrial function with age, a process that is apparently reversible.”
[5] David Cameron, “A New—and Reversible—Cause of Aging,” Harvard Medical School, December 19, 2013.
[6] Ibid.
[7] The matter of brain transplants puts this assumption at risk, for a brain grown out of some cells would not have the memories. Stretching the envelop even more, what if science eventually enables the memories and even consciousness of the “old” brain to be part of the brain being grown? It seems more likely that the experiential continuity of the person would continue.